Hepatitis may be caused by a viral infection, or it may result from sensitivity to a hepatotoxic drug or chemical, from chronic excessive alcohol consumption, or from autoimmune factors. It can be acute, chronic, or fulminant. People with viral hepatitis can be carriers in that they transmit the virus but have no evidence of infection themselves. Hepatitis may also be in an active or dormant state. There are currently five types of viral hepatitis known, and two types are currently undergoing further research. Hepatitis and its sequelae affect more than 500 million people worldwide. Both sexes and all age groups are equally affected. Hepatitis can cause cirrhosis or liver cancer, and it is the underlying basis for most liver transplants.
Prodromal phase: viral symptoms such as nausea, vomiting, malaise, anorexia, low-grade fever, headache; 2 weeks after exposure to virus, which ends with the onset of jaundice
Icteric phase: jaundice, dark tea-colored urine or clay-colored stools, hepatomegaly and right upper quadrant pain; begins 1-2 weeks after prodromal phase and lasts up to 6 weeks
Recovery phase: resolution of jaundice approximately 6-8 weeks after exposure; liver may remain enlarged for up to 3 months
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