
(fin as’ teh ride)
Propecia, Proscar
PREGNANCY CATEGORY X
Drug Class
Androgen hormone inhibitor
Therapeutic Actions
Inhibits the intracellular enzyme that converts testosterone into a potent androgen (DHT); does not affect androgen receptors in the body; the prostate gland depends on DHT for its development and maintenance.
Indications
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Proscar: Treatment of symptomatic BPH; most effective with long-term use; reduces the need for prostate surgery and reduces the risk of urinary retention; with doxazosin, to reduce the risk of progression of BPH symptoms
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Propecia: Prevention of male pattern baldness (androgenetic alopecia) in patients with family history or early signs of loss
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Unlabeled uses: Adjuvant monotherapy following radical prostatectomy; prevention of the progression of first-stage prostate cancer; hirsutism; male chronic pelvic pain syndrome
Contraindications and Cautions
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Contraindicated with allergy to finasteride or any component of the product, pregnancy, lactation.
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Use cautiously with hepatic impairment.
Available Forms
Tablets—1 mg (Proecia), 5 mg (Proscar)
Dosages
Adults
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BPH: 5 mg daily PO with or without meals; may take 6–12 mo for response (Proscar).
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