Dangerous Drug: Opium Preparations

Dangerous Drug: Opium Preparations
(oh’ pee um)
Camphorated tincture: Paregoric
Deodorized tincture: Opium Tincture, Deodorized
CONTROLLED SUBSTANCE C-III (PAREGORIC)
CONTROLLED SUBSTANCE C-II (OPIUM TINCTURE, DEODORIZED)
PREGNANCY CATEGORY C
Drug Classes
Antidiarrheal
Opioid agonist analgesic
Therapeutic Actions
Activity is primarily due to morphine content; acts as agonist at specific opioid receptors in the CNS to produce analgesia, euphoria, sedation; the receptors mediating these effects are thought to be the same as those mediating the effects of endogenous opioids (enkephalins, endorphins); inhibits peristalsis and diarrhea by producing spasm of GI tract smooth muscle.
Indications
  • Antidiarrheal
  • Unlabeled uses: Neonatal abstinence syndrome, management of short-bowel syndrome
Available Forms
Liquid—2 mg morphine equivalent/5 mL (Paregoric); 10 mg/mL (Opium Tincture, Deodorized)
Dosages
Warning Caution: Opium Tincture, Deodorized, contains 25 times more morphine than Paregoric. Do not confuse dosage; severe toxicity can occur.
Adults
Paregoric
5–10 mL PO daily–qid (5 mL is equivalent to 2 mg morphine).
Opium Tincture, Deodorized

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Jul 21, 2016 | Posted by in NURSING | Comments Off on Dangerous Drug: Opium Preparations

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