Colestipol Hydrochloride

Colestipol Hydrochloride
(koe les’ ti pole)
Colestid
PREGNANCY CATEGORY C
Drug Classes
Antihyperlipidemic
Bile acid sequestrant
Therapeutic Actions
Binds bile acids in the intestine to form a complex that is excreted in the feces; as a result, cholesterol is lost, oxidized in the liver, and serum cholesterol and LDL are lowered.
Indications
  • Adjunctive therapy: Reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated LDL)
  • Unlabeled uses: Digitalis toxicity, hyperoxaluria, relief of pruritus associated with biliary obstruction, adjunctive treatment of hyperthyroidism, binding of Clostridium difficile toxin
Available Forms
Tablets—1 g; granules—5-g powder/dose
Dosages
Adults
For suspension, 5–30 g/day PO once or in divided doses two to four times/day. Start with 5 g daily or bid PO, and increase in 5-g/day increments at 1- to 2-mo intervals. For tablets, 2–16 g/day PO in 1–2 divided doses; initially, 2 g once or twice daily; increasing in 2-g increments at 1- to 2-mo intervals.
Pediatric patients
Safety and efficacy not established.

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Jul 20, 2016 | Posted by in NURSING | Comments Off on Colestipol Hydrochloride

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