Chorionic Gonadotropin (Human Chorionic Gonadotropin, HCG)(kor e awn ick goe nad’ oh troe pin)
Novarel, Pregnyl
PREGNANCY CATEGORY X
Drug Classes
Hormone
Therapeutic Actions
A human placental hormone with actions identical to pituitary LH; stimulates production of testosterone and progesterone.
Indications
Prepubertal cryptorchidism not due to anatomic obstruction
Treatment of selected cases of hypogonadotropic hypogonadism in males
Induction of ovulation in the anovulatory, infertile woman in whom the cause of anovulation is secondary and not due to primary ovarian failure and who has been pretreated with human menotropins
Available Forms
Powder for injection—10,000 units/vial with 10 mL diluent
Dosages
Patients older than 4 yr
For IM use only; individualize dosage; the following dosage regimens are suggested
Prepubertal cryptorchidism not due to anatomic obstruction: 4,000 USP units IM, three times per week for 3 wk; 5,000 USP units IM, every second day for 4 injections; 15 injections of 500–1,000 USP units over 6 wk; 500 USP units three times per week for 4–6 wk; if not successful, start another course 1 mo later, giving 1,000 USP units/injection.
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