Chlorzoxazone(klor zox’ a zone)
Paraflex, Parafon Forte DSC, Remular-S
PREGNANCY CATEGORY C
Drug Classes
Skeletal muscle relaxant (centrally acting)
Therapeutic Actions
Precise mechanism not known; has sedative properties; acts at spinal and supraspinal levels of the CNS to depress reflex arcs involved in producing and maintaining skeletal muscle spasm.
Indications
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Relief of discomfort associated with acute, painful musculoskeletal conditions, adjunct to rest, physical therapy, and other measures
Contraindications and Cautions
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Contraindicated with allergic or idiosyncratic reactions to chlorzoxazone.
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Use cautiously with history of allergies or allergic drug reactions, lactation, pregnancy.
Available Forms
Tablets—250, 375, 500, 750 mg
Dosages
Adults
Usual dose, 250 mg PO tid–qid; painful conditions may require 500 mg PO tid–qid; may increase to 750 mg tid–qid; reduce dosage as improvement occurs.
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