Chlorpheniramine Maleate(klor fen ir’ a meen mal’ ee ate)
Aller-Chlor; Allergy; Allergy Relief; Chlo-Amine; Chlor-Trimeton Allergy 8 hr, and 12 hr; ED-CHLOR-TANDNC; QDALL-ARDNC
PREGNANCY CATEGORY C
Drug Classes
Antihistamine (alkylamine type)
Therapeutic Actions
Competitively blocks the effects of histamine at H1-receptor sites; has atropine-like, antipruritic, and sedative effects.
Indications
-
Symptomatic relief of symptoms associated with perennial and seasonal allergic rhinitis; vasomotor rhinitis; common cold; allergic conjunctivitis
Contraindications and Cautions
-
Use cautiously in pregnancy, geriatric patients.
Available Forms
Chewable tablets—2 mg; tablets—4 mg; ER tabletsDNC—8, 12, 16 mg; syrup—2 mg/5 mL; SR capsulesDNC—8, 12 mg; ER capsulesDNC—12 mg; caplets—8 mg
Dosages
Adults and children older than 12 yr
Tablets or syrup
4 mg PO every 4–6 hr; do not exceed 24 mg in 24 hr.
SR
8–12 mg PO at bedtime or every 8–12 hr during the day; do not exceed 24 mg in 24 hr.
ER capsules
12 mg/day PO; do not exceed 24 mg/day.
Caplets
8–12 mg/day PO every 12 hr.
Pediatric patients
Tablets or syrup
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