Cetirizine Hydrochloride(se teer’ i zeen)
Reactine (CAN), Zyrtec, Zyrtec Allergy, Zyrtec Children’s Allergy, Zyrtec Children’s Hives Relief, Zyrtec Hives Relief
PREGNANCY CATEGORY B
Drug Class
Antihistamine
Therapeutic Actions
Potent specific histamine (H1) receptor antagonist; inhibits histamine release and eosinophil chemotaxis during inflammation, leading to reduced swelling and decreased inflammatory response.
Indications
Management of seasonal and perennial allergic rhinitis, allergies, hay fever
Treatment of chronic, idiopathic urticaria
Unlabeled uses: To decrease wheal response and pruritus of mosquito bites; possible use in allergic asthma
Contraindications and Cautions
Contraindicated with allergy to antihistamines, hydroxyzine.
Use cautiously with narrow-angle glaucoma, stenosing peptic ulcer, symptomatic prostatic hypertrophy, asthmatic attack, bladder neck obstruction, pyloroduodenal obstruction (avoid use or use with caution as condition may be exacerbated by drug effects); lactation.
Available Forms
Tablets—5, 10 mg; chewable tablets—5, 10 mg; capsules—10 mg; syrup—1 mg/mL
Dosages
Adults and children 6 yr and older
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