Characterized by poor food absorption and intolerance of gluten — a protein found in grains, such as wheat, rye, oats, and barley

Usually becomes apparent between ages 6 and 18 months

The amount and activity of enzymes in the intestinal mucosal cells is decreased.

Villi of the proximal small intestine atrophy, decreasing intestinal absorption.

Gluten intolerance

Immunoglobulin A deficiency

Steatorrhea (fatty stools)

Chronic diarrhea

Anorexia

Generalized malnutrition and failure to thrive