Ceftazidime(sef taz’ i deem)
Ceptaz, Fortaz, Tazicef
PREGNANCY CATEGORY B
Drug Classes
Antibiotic
Cephalosporin (third generation)
Therapeutic Actions
Bactericidal: Inhibits synthesis of bacterial cell wall, causing cell death.
Indications
Lower respiratory infections caused by Pseudomonas aeruginosa, other Pseudomonas, Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella, Haemophilus influenzae, Proteus mirabilis, Escherichia coli, Enterobacter, Serratia, Citrobacter
UTIs caused by P. aeruginosa, Enterobacter, E. coli, Klebsiella, P. mirabilis, Proteus
Gynecologic infections caused by E. coli
Skin and skin structure infections caused by P. aeruginosa, S. aureus, E. coli, Serratia, Proteus, Klebsiella, Enterobacter, Streptococcus pyogenes
Septicemia caused by P. aeruginosa, E. coli, Klebsiella, H. influenzae, Serratia, S. pneumoniae, S. aureus
Intra-abdominal infections caused by E. coli, S. aureus, Bacteroides, Klebsiella
CNS infections caused by H. influenzae, Neisseria meningitidis
Bone and joint infections caused by P. aeruginosa, Klebsiella, Enterobacter, S. aureus
Unlabeled use: Catheter-related bloodstream infections in children and adolescents
Contraindications and Cautions
Contraindicated with allergy to cephalosporins or penicillins.
Use cautiously with renal failure, lactation, pregnancy.
Available Forms
Powder for injection—500 mg, 1, 2 g; injection—1, 2 g
Dosages
Adults
Usual dose, 1 g (range 250 mg–2 g) every 8–12 hr IM or IV. Do not exceed 6 g/day. Dosage will vary with infection.
UTI: 250–500 mg IV or IM every 8–12 hr.
Pneumonia, skin and skin structure infections: 500 mg–1 g IV or IM every 8 hr.
Bone and joint infections: 2 g IV every 12 hr.
Gynecologic, intra-abdominal, life-threatening infections, meningitis: 2 g IV every 8 hr.
Pediatric patients 1 mo–12 yr
30–50 mg/kg IV every 8 hr. Do not exceed 6 g/day.
Pediatric patients 0–4 wk
Stay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree
