Cefdinir(sef’ din er)
PREGNANCY CATEGORY B
Drug Classes
Antibiotic
Cephalosporin (third generation)
Therapeutic Actions
Bactericidal: Inhibits synthesis of bacterial cell wall, causing cell death.
Indications
Adults and adolescents
Community-acquired pneumonia caused by Haemophilus influenzae, Haemophilus parainfluenzae, Streptococcus pneumoniae, Moraxella catarrhalis
Acute exacerbations of chronic bronchitis caused by H. influenzae, H. parainfluenzae, S. pneumoniae, M. catarrhalis
Acute maxillary sinusitis caused by H. influenzae, S. pneumoniae, M. catarrhalis
Pharyngitis and tonsillitis caused by Streptococcus pyogenes
Uncomplicated skin and skin structure infections caused by Staphylococcus aureus, S. pyogenes
Pediatric patients
Acute bacterial otitis media caused by H. influenzae, S. pneumoniae, M. catarrhalis
Pharyngitis and tonsillitis caused by S. pyogenes
Uncomplicated skin and skin-structure infections caused by S. aureus, S. pyogenes
Contraindications and Cautions
Contraindicated with allergy to cephalosporins or penicillins.
Use cautiously with renal failure, lactation, pregnancy.
Available Forms
Capsules—300 mg; oral suspension—125 mg/5 mL; 250 mg/5 mL
Dosages
Adults and adolescent patients
Community-acquired pneumonia, uncomplicated skin or skin-structure infections: 300 mg PO every 12 hr for 10 days.
Acute exacerbation of chronic bronchitis, acute maxillary sinusitis, pharyngitis, or tonsillitis: 300 mg every 12 hr PO for 5–10 days or 600 mg every 24 hr PO for 10 days.
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