Antimigraine Drugs (Triptans)
PREGNANCY CATEGORY C
Therapeutic Actions
Triptans bind to serotonin receptors to cause vascular constrictive effects on cranial blood vessels, causing the relief of migraine in selective patients.
Indications
Treatment of acute migraine attacks with or without aura
Treatment of cluster headaches (sumatriptan injection)
Contraindications and Cautions
Contraindicated with allergy to any triptan, active coronary artery disease, uncontrolled hypertension, hemiplegic migraine, pregnancy.
Use cautiously in the elderly; with lactation.
Adverse Effects
CNS: Dizziness, vertigo, headache, anxiety, malaise or fatigue, weakness, myalgia
CV: BP alterations, tightness or pressure in chest, MI
GI: Abdominal discomfort, dysphagia
Local: Injection site discomfort
Other: Tingling, warm or hot sensations, burning sensation, feeling of heaviness, pressure sensation, numbness, feeling of tightness, feeling strange, cold sensation
Stay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree
