Antianginal Drugs



Antianginal Drugs















Table 41-1 Antianginal Drugs



















Prototype Drug


Related Drugs


Drug Classification


nitroglycerin (Nitro-bid, Nitrostat, others)


amyl nitrite isosorbide dinitrate (Isordil, Sorbitrate) isosorbide mononitrate (Imdur, ISMO)


Nitrates


propranolol (Inderal)


atenolol (Tenormin) metoprolol (Lopressor) nadolol (Corgard)


Beta-blockers


nifedipine (Procardia)


amlodipine (Norvasc) bepridil (Vascor) diltiazem (Cardizem) felodipine (Plendil) isradipine (Dynacirc) nicardipine (Cardene) nimodipine (Nimotop) nisoldipine (Sular) verapamil (Calan)


Calcium channel blockers



ANTIANGINAL DRUGS CLIENT TEACHING


Nitrates



  • Change positions gradually to avoid orthostatic hypotension.


  • Nitroglycerin can lose potency if exposed to light, moisture, or heat.


  • Replace tablets 6 months after opening, as nitrates lose potency over time.


  • Avoid alcohol, hot baths, saunas, and whirlpools, as they can cause vasodilatation and lead to hypotension and fainting.


  • Teach side effects and adverse effects of nitrates, which include headaches (that can last up to 20 minutes), dizziness, facial flushing, increased heart rate, and lightheadedness.



  • Report to health care provider if dry mouth, severe headaches, or blurred vision occur.


  • An analgesic can be given to treat headache.


  • Discard cotton packing after opening bottle, as the packing may absorb the drug and lead to decreased potency.


  • Encourage client to discontinue tobacco use, as tobacco causes vasoconstriction.


  • Avoid OTC and herbal remedies without first consulting health care provider.


  • Keep a journal documenting number and characteristics of anginal attacks, contributing factors and number of tablets taken, and adverse effects.





Sublingual Tablets



  • If client has an acute anginal attack, teach client to lie down and take SL tablet as soon as possible; up to 3 nitroglycerin tablets every 5 minutes for 15 minutes may be taken; if no relief, emergency services should be notified for transport to the emergency room.


  • Do not chew SL tablets. Place under tongue to dissolve. Do not swallow tablet.


  • Tablet should burn slightly under the tongue, if not replace supply of tablets.4


  • Do not eat food or smoke until tablet dissolves.



Buccal



  • Place tablet between upper lip and gum to dissolve.



Chewable Tablets



  • Chew thoroughly and hold in mouth 2 minutes before swallowing.


Oral Sustained-Release Tablets or Capsules

Oct 21, 2016 | Posted by in NURSING | Comments Off on Antianginal Drugs

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